Bj. Gallay et al., GLOMERULONEPHRITIS IN RENAL-ALLOGRAFTS ASSOCIATED WITH HEPATITIS-C INFECTION - A POSSIBLE RELATIONSHIP WITH TRANSPLANT GLOMERULOPATHY IN 2 CASES, American journal of kidney diseases, 26(4), 1995, pp. 662-667
Chronic infection with hepatitis C virus (HCV) has been identified as
a cause of type I membranoproliferative glomerulonephritis (MPGN), HCV
infection is common in patients with end-stage renal disease and may
persist in renal allograft recipients, MPGN in the allograft may there
fore be a manifestation of persistent HCV infection, We report two cas
es of glomerulopathy with features of both MPGN and transplant glomeru
lopathy in renal transplant patients chronically infected with HCV, We
discuss the course of interferon alfa therapy in both patients as wel
l as a possible relationship of HCV infection with transplant glomerul
opathy (C) 1995 by the National Kidney Foundation, Inc.