Not only has our understanding of cartilage structure, synthesis and b
reakdown increased over the last decade, but so have the possibilities
for investigation and treatment of osteoarthritis. New strategies for
investigation include ultrasound, magnetic resonance imaging, radionu
clide scintigraphy, monitoring of biochemical markers for cartilage br
eakdown and miniarthroscopy. There is greater appreciation of the impo
rtance of exercise and analgesics in pain management, and drugs to ret
ard cartilage breakdown are under development.