T. Kiyosawa et al., HEREDITARY MULTIPLE GLOMUS TUMORS INVOLVING THE GLANS-PENIS - A CASE-REPORT AND REVIEW OF THE LITERATURE, Dermatologic surgery, 21(10), 1995, pp. 895-899
BACKGROUND. Multiple tumors are extremely rare and seldom demonstrate
malignant change. OBJECTIVE. To describe an exceptionally rare case of
familial multiple glomus tumors involving the glans penis. METHOD. Mu
ltiple glomus tumors in a father and son were studied by light and ele
ctron microscopy. RESULTS. The clinical presentation of the two patien
ts was similar, and atypical glomus cells were identified in both son
and father. The histology of the tumor cells suggested that they were
malignant, yet the clinical course has been benign. CONCLUSION. Despit
e their malignant histologic appearance, the behavior of familial glom
us tumors is benign. A conservative approach to treatment appears warr
anted. The diagnosis an management of these lesions should be based on
clinical behavior rather than histopathology.