4-(ACETYLAMINO)-3-HYDROXY-5-NITROBENZOIC ACID

Authors
JEDRZEJAS MJ LUO M SINGH S BROUILLETE WJ AIR GM
Citation
Mj. Jedrzejas et al., 4-(ACETYLAMINO)-3-HYDROXY-5-NITROBENZOIC ACID, Acta crystallographica. Section C, Crystal structure communications, 51, 1995, pp. 1910-1912
Citations number
24
Categorie Soggetti
Crystallography
Journal title
Acta crystallographica. Section C, Crystal structure communications → ACNP
ISSN journal
01082701
Volume
51
Year of publication
1995
Part
9
Pages
1910 - 1912
Database
ISI
SICI code
0108-2701(1995)51:<1910:4A>2.0.ZU;2-G
Abstract
The 4-(acetylamino)-3-hydroxy-5-nitrobenzoic acid molecule, C9H8N2O6, a designed inhibitor for the influenza virus neuraminidase protein, cr ystallizes as hydrogen-bonded dimers. The dihedral angles of the subst ituent groups with respect to the planar phenyl moiety are 5.0(3)degre es for the carboxyl group, 45.0(2)degrees for the nitro group and 37.3 (1)degrees for the acetylamino substituent. The crystal structure is s tabilized by intermolecular hydrogen bonding.