Biomechanics of cerebral trauma attempts to delineate the dynamic resp
onse of the cranial vault contents to a direct or indirect impact to t
he head. Consequently, brain injury mechanisms and associated toleranc
e to impact can be deduced by establishing a relationship between neur
ological deficit and mechanical dosage. The resulting information is i
nvaluable to brain injury prevention and diagnosis. This paper present
s an overview of our recent research on head injury focusing on establ
ishing brain injury biomechanics by developing a comprehensive and val
idated mathematical model. To achieve our goal, we developed a compreh
ensive three-dimensional finite element human head model, finite eleme
nt porcine head models, and sensors to monitor head kinematics and bra
in strains by neutral density accelerometers. The information obtained
from this research thus far provided a predictive and somewhat valida
ted mathematical model of the head, which clearly shows a corresponden
ce between brain mechanical response and experimentally observed injur
ies.