ORGANIZATION OF A MIDLINE PROLIFERATIVE CLUSTER IN THE EMBRYONIC BRAIN OF THE GRASSHOPPER

Citation
Gs. Boyan et al., ORGANIZATION OF A MIDLINE PROLIFERATIVE CLUSTER IN THE EMBRYONIC BRAIN OF THE GRASSHOPPER, Roux's archives of developmental biology, 205(1-2), 1995, pp. 45-53
Citations number
35
Categorie Soggetti
Developmental Biology
ISSN journal
0930035X
Volume
205
Issue
1-2
Year of publication
1995
Pages
45 - 53
Database
ISI
SICI code
0930-035X(1995)205:1-2<45:OOAMPC>2.0.ZU;2-J
Abstract
We have studied a group of midline cells in the embryonic brain of the grasshopper by using immunocytochemical and intracellular dye injecti on techniques. This cluster of midline cells differentiates between th e pars intercerebralis lobes of the protocerebrum during early embryog enesis, and is composed of putative midline progenitors as well as neu ronal and glial cells. Annulin immunoreactive glial processes surround the borders of the midline cell cluster and also form a network of pr ocesses extending from there to the borders of proliferative clusters in the brain hemispheres. Among the cells that derive from the midline cluster are two bilaterally symmetrical pairs of identified primary c ommissure pioneer neurons. By navigating along the glial-bound borders of the midline proliferative cluster, the axons of these pioneers est ablish an initial axonal bridge across the brain midline. This analysi s identifies a glial-bound midline proliferative cluster in the brain and shows that neuronal and glial cells of this cluster are closely as sociated with neurons pioneering the primary brain commissure. Compara ble features of midline cells in the ventral ganglia and similarities to other proliferative clusters in the brain hemispheres are discussed .