MOLECULAR DIVERSITY OF DOPAMINE D1-LIKE RECEPTORS IN THE EUROPEAN EEL

Three subtypes of D1-like receptors in the brain of the European ecl, Anguilla anguilla, were isolated through cDNA cloning. Two D1a-like tr anscripts (Anguilla D1 and D1 PCR) and one D1b/D5-like transcript (Ang uilla D5) are expressed. In situ hybridization performed with the Angu illa D1 PCR cRNA as a probe revealed that the corresponding mRNA occur s in most of the dopamine target areas and mainly in regions near the ventricles.