Mer. Williamson et al., CLINICAL AND PHYSIOLOGICAL EVALUATION OF ANORECTAL EVERSION DURING RESTORATIVE PROCTOCOLECTOMY, British Journal of Surgery, 82(10), 1995, pp. 1391-1394
Fifty patients had a restorative proctocolectomy with stapled end-to-e
nd ileoanal anastomosis by the eversion technique. Median (interquarti
le range) maximum resting anal pressure was 90 (73-116) cmH(2)O before
restorative proctocolectomy and 71 (51-88)cmH(2)O 1 year after surger
y (P<0.001). Median maximum squeeze pressure was 141 (110-185)cmH(2)O
before surgery and 146 (118-186) cmH(2)O 1 year after surgery (P not s
ignificant). Median thresholds for sensation in the lower third of the
anal canal before and 1 year after surgery were 5.3 and 7.1 mA, respe
ctively (P=0.006). One year after restorative proctocolectomy, all pat
ients were continent, although two experienced leakage of mucus requir
ing a pad. Forty-two patients (84 per cent) could discriminate between
faeces and flatus. Eversion of the anorectum during restorative proct
ocolectomy impairs the motor and sensory functions of the anal sphinct
er. Most patients achieved satisfactory anal continence, however, desp
ite these physiological changes.