HEMOPHAGOCYTOSIS - A COMPLICATION OF ACUTE Q-FEVER IN A CHILD

Authors
HUFNAGEL M NIEMEYER C ZIMMERHACKL LB TUCHELMANN T SAUTER S BRANDIS M
Citation
M. Hufnagel et al., HEMOPHAGOCYTOSIS - A COMPLICATION OF ACUTE Q-FEVER IN A CHILD, Clinical infectious diseases, 21(4), 1995, pp. 1029-1031
Citations number
10
Categorie Soggetti
Microbiology,Immunology,"Infectious Diseases
Journal title
Clinical infectious diseases → ACNP
ISSN journal
10584838
Volume
21
Issue
4
Year of publication
1995
Pages
1029 - 1031
Database
ISI
SICI code
1058-4838(1995)21:4<1029:H-ACOA>2.0.ZU;2-B
Abstract
We describe an Ii-year-old boy with acute Q fever complicated by hemop hagocytosis. In addition to pancytopenia, the boy presented with hypon atremia, hypofibrinogenemia, and changes in lipid metabolism. Examinat ion of a bone marrow aspirate revealed striking hemophagocytosis. All of the pathological changes were caused by an activated macrophage sys tem. We also discuss the possible role that pathogenetic mechanisms pl ay in these changes.