PHOTOCHEMISTRY OF SUBSTITUTED PROPIOPHENONES - AN INTERESTING ALPHA-SUBSTITUENTS AND ARYL-SUBSTITUENTS EFFECT ON THEIR PHOTOBEHAVIOR

Photochemistry of different alpha-substituted and phenyl-substituted p ropiophenones in methanol is investigated with a view to delineate the substituent effect with a special reference to their rearrangement to alpha-arylpropanoic acids, an important class of nonsteroidal antiinf lammatory agents. The results thus obtained bringsforth an important e lement of their reactivity profile i.e. the alpha-chloro-substituent i n combination with nuclear alkyl substituents (para > meta) favours 1, 2-arylmigration leading to the synthetically useful reaction for alpha -arylpropanoic acids.