Histological analysis of an abnormal neck mass has traditionally requi
red an excision biopsy under general anaesthetic, We evaluated the saf
ety and accuracy of a new spring loaded cutting-needle for obtaining t
issues cores of neck masses under ultrasound (US) guidance. Sixty biop
sies were performed on an outpatient basis under local anaesthesia in
52 patients referred with a neck mass, Patients ranged in age from 10
months to 89 years and masses varied in size from 5mm to 5cm. Fifty-ei
ght of the 60 biopsies provided a diagnostic histological specimen, Of
the remaining two patients, one required open biopsy and the other re
turned for a second needle biopsy, All five cases of lymphoma were cor
rectly diagnosed on needle biopsy; in three cases full tumour sub-clas
sification was possible but in two patients an open biopsy was subsequ
ently required, in 39 patients the needle biopsy obviated the need for
a surgical biopsy for diagnostic purposes, although in 12 cases a the
rapeutic excision biopsy was performed. Apart from one subclinical hae
matoma, visualized on US, there were no immediate or delayed complicat
ions, In all patients, the histological diagnosis was compatible with
subsequent clinical, radiological, surgical or autopsy findings. Cutti
ng-needle biopsy of neck masses under US guidance is an effective and
safe procedure which should be considered before resorting to routine
surgery.