COLON PERFORATION IN A PATIENT WITH HYPERIMMUNOGLOBULIN-E (JOB)-SYNDROME

A Taiwanese boy was diagnosed as having hyperimmunoglobulin E syndrome at the age of 4 years. At age 18 he was admitted to the hospital beca use of pneumonia in tile left lower lobe. Abdominal pain developed 9 d ays later, and his condition progressed to peritonitis. Colon perforat ion, 10 cm distal to the ileocecal valve, was found. Double-barrel ile ostomy was performed, and reanastomosis was done 11/2 months later. Af terward, he was fine, and he had no significant gastrointestinal probl ems after being discharged. To the authors' knowledge, this is the fir st reported case of hyperimmunoglobulin E syndrome complicated by colo n perforation. Copyright (C) 1995 by W.B. Saunders Company.