Gq. Shi et Zy. Cao, ETHYL 2-BENZYLOXY-3,3-DIFLUOROPROPENOATE AS A NOVEL SYNTHON OF BETA-FLUORO-ALPHA-KETO ACID-DERIVATIVES, PREPARATION AND REACTIONS WITH NUCLEOPHILES, Journal of the Chemical Society, Chemical Communications, (19), 1995, pp. 1969-1970
Ethyl 2-benzyloxy-3,3-difluoropropenoate 3, prepared from the readily
obtainable ethyl trifluoropyruvate, reacts with a variety of nucleophi
les to give beta-fluoro-alpha-keto acid derivatives in high yield.