ETHYL 2-BENZYLOXY-3,3-DIFLUOROPROPENOATE AS A NOVEL SYNTHON OF BETA-FLUORO-ALPHA-KETO ACID-DERIVATIVES, PREPARATION AND REACTIONS WITH NUCLEOPHILES

Authors
Citation
Gq. Shi et Zy. Cao, ETHYL 2-BENZYLOXY-3,3-DIFLUOROPROPENOATE AS A NOVEL SYNTHON OF BETA-FLUORO-ALPHA-KETO ACID-DERIVATIVES, PREPARATION AND REACTIONS WITH NUCLEOPHILES, Journal of the Chemical Society, Chemical Communications, (19), 1995, pp. 1969-1970
Citations number
19
Categorie Soggetti
Chemistry
ISSN journal
00224936
Issue
19
Year of publication
1995
Pages
1969 - 1970
Database
ISI
SICI code
0022-4936(1995):19<1969:E2AANS>2.0.ZU;2-T
Abstract
Ethyl 2-benzyloxy-3,3-difluoropropenoate 3, prepared from the readily obtainable ethyl trifluoropyruvate, reacts with a variety of nucleophi les to give beta-fluoro-alpha-keto acid derivatives in high yield.