K. Hu et al., SCREENING ASSAY FOR DIOXIN-LIKE COMPOUNDS BASED ON COMPETITIVE-BINDING TO THE MURINE HEPATIC AH RECEPTOR .2. APPLICATION TO ENVIRONMENTAL-SAMPLES, Environmental science & technology, 29(10), 1995, pp. 2603-2609
A series of environmental samples, comprising fly ash, caustic wash wa
ter from regeneration of a petrochemical reforming catalyst,fish homog
enates, soil, and pulp mill sludge, were analyzed for dioxin-like comp
ounds by an assay involving competitive binding of a reference radioli
gand and an extract from the sample to mouse hepatic Ah receptor; the
results were compared with GC/MS. The bioassay generally gave higher T
EQ values than GC/MS, further analysis by GC/MS in most cases identifi
ed much of the additional Ah receptor-active material as coplanar PCBs
and PAHs.