This review paper deals with the characteristics and properties of rep
roductive system, mammmary gland and placental barrier for drug transf
er in pigs, and the adverse effects of drugs. The undesirable effect e
valuation of drugs acting on the reproductive system (regulators of fe
rtility, promoters of gonadal function, sex hormones, prostaglandins,
myometrial stimulants and relaxants) and those used for uterine and ma
mmary infections and for disorders of the urinary tract is described.
In addition, some food contaminants that affect the reproductive syste
m in pigs are also included.