J. Caravalho et al., LOCALIZATION OF AN ECTOPIC PARATHYROID ADENOMA BY DOUBLE-PHASE TECHNETIUM-99M-SESTAMIBI SCINTIGRAPHY, The Journal of nuclear medicine, 36(10), 1995, pp. 1840-1842
Double-phase planar scintigraphy using Tc-99m-MIBI has been introduced
as a means to detect and localize parathyroid adenomas. Focal uptake
on both early and delayed imaging is typical of these entities. We rep
ort a patient with persistent hypercalcemia following subtotal parathy
roidectomy, who was found scintigraphically to have an ectopic parathy
roid adenoma. Following initial detection within the mediastinum using
planar scintigraphy, the adenoma was more precisely localized using S
PECT imaging. This case suggests that double-phase parathyroid planar
scintigraphy augmented with SPECT imaging, if needed, is cost-effectiv
e, and often necessary, in the assessment of primary hyperparathyroid
patients before surgical reexploration.