Background - Asthma outbreaks have not been detected in Barcelona, Spa
in since the epidemic of 1981-7. On 29 October 1994 several subjects a
ttended a Barcelona because of acute attacks of and were identified as
former soybean epidemic asthma patients (repeaters), raising the poss
ibility of an asthma soybean-related episode. The usefulness of counti
ng repeaters to evaluate small increases of acute asthma in a nonepide
mic period is illustrated. Methods - A retrospective identification of
asthma admissions was performed, pollution filters collected before a
nd after the index day were analysed for contents of low molecular wei
ght soybean allergen, and soybean unloading activities were investigat
ed. Results - There was no epidemic increase of asthma patients during
this day in the whole of Barcelona, but an unusually high number were
repeaters (seven observed v 0.483 expected). A relationship with incr
eased levels of low molecular weight soybean allergen (U/m(3)) was det
ected in the available pollution filters collected the day before and
after the index day. Two ships were unloading soybean in the city harb
our on the index day. Conclusion - Soybean unloading at the harbour of
Barcelona released soybean dust and produced a small cluster of emerg
ency room visits for asthma in patients formerly affected by soybean a
sthma epidemics. It is suggested that counting repeaters could provide
the basis for a systematic epidemiological surveillance of sensitised
populations.