SYNTHESIS OF 2-DEOXY-2-FLUORINATED INOSITOL-1-O-DODECYLPHOSPHONATES AS INHIBITORS OF GLYCOSYL PHOSPHATIDYLINOSITOL PHOSPHOLIPASE-C

Authors
ZHAI HX LEI PS MORRIS JC MENSAWILMOT K SHEN TY
Citation
Hx. Zhai et al., SYNTHESIS OF 2-DEOXY-2-FLUORINATED INOSITOL-1-O-DODECYLPHOSPHONATES AS INHIBITORS OF GLYCOSYL PHOSPHATIDYLINOSITOL PHOSPHOLIPASE-C, Tetrahedron letters, 36(41), 1995, pp. 7403-7406
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
41
Year of publication
1995
Pages
7403 - 7406
Database
ISI
SICI code
0040-4039(1995)36:41<7403:SO2IA>2.0.ZU;2-8
Abstract
Three 2-deoxy-2-fluorinated inositols and their 1-O-dodecylphosphonate derivatives have been synthesized as non-cleavable inhibitors of glyc osyl phosphatidylinositol phospholipase C. Their structure-activity re lationship is discussed.