2 NEW METHODS FOR 2,3-PYRIDYNE FORMATION

Authors
WALTERS MA SHAY JJ
Citation
Ma. Walters et Jj. Shay, 2 NEW METHODS FOR 2,3-PYRIDYNE FORMATION, Tetrahedron letters, 36(42), 1995, pp. 7575-7578
Citations number
37
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
42
Year of publication
1995
Pages
7575 - 7578
Database
ISI
SICI code
0040-4039(1995)36:42<7575:2NMF2F>2.0.ZU;2-B
Abstract
The compounds 2-chloro-4-methoxypyridine and rifluoromethylsulfonyloxy -3-trimethylsilylpyridine were shown to be relatively efficient precur sors for 4-methoxy-2,3-pyridyne as was evidenced by its napping with f uran, 2-methylfuran and 2-methoxyfuran. These findings constitute the first published report of the use of either directed-deprotonation or fluoride-induced elimination to prepare the reactive 2,3-pyridyne inte rmediate.