7-AMIDO-1,8-NAPHTHYRIDINES AS HYDROGEN-BONDING UNITS FOR THE COMPLEXATION OF GUANINE DERIVATIVES - THE ROLE OF 2-ALKOXYL GROUPS IN DECREASING BINDING-AFFINITY

Citation
Tj. Murray et Sc. Zimmerman, 7-AMIDO-1,8-NAPHTHYRIDINES AS HYDROGEN-BONDING UNITS FOR THE COMPLEXATION OF GUANINE DERIVATIVES - THE ROLE OF 2-ALKOXYL GROUPS IN DECREASING BINDING-AFFINITY, Tetrahedron letters, 36(42), 1995, pp. 7627-7630
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
00404039
Volume
36
Issue
42
Year of publication
1995
Pages
7627 - 7630
Database
ISI
SICI code
0040-4039(1995)36:42<7627:7AHUFT>2.0.ZU;2-#
Abstract
The unusually low stability of a hydrogen bonded complex between a gua nosine derivative and a 7-amido-2-alkoxy-1,8-naphthyridine, containing the DAA . ADD motif, can be explained by a conformational/steric effe ct.