REACTION OF RUPPERT REAGENT (TMS-CF3) WITH OXAZOLIDINONES - SYNTHESISOF PROTECTED ALPHA-AMINO TRIFLUOROMETHYLKETONES

Authors
WALTER MW ADLINGTON RM BALDWIN JE CHUHAN J SCHOFIELD CJ
Citation
Mw. Walter et al., REACTION OF RUPPERT REAGENT (TMS-CF3) WITH OXAZOLIDINONES - SYNTHESISOF PROTECTED ALPHA-AMINO TRIFLUOROMETHYLKETONES, Tetrahedron letters, 36(42), 1995, pp. 7761-7764
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
42
Year of publication
1995
Pages
7761 - 7764
Database
ISI
SICI code
0040-4039(1995)36:42<7761:RORR(W>2.0.ZU;2-A
Abstract
(Trifluoromethyl)trimethylsilane adds to alpha-amino acid derived oxaz olidin-5-ones in excellent yields. The adducts can be converted into p rotected alpha-amino trifluoromethylketones by acid hydrolysis.