Two full-length cDNA clones encoding rabbit glyceraldehyde-3-phosphate
dehydrogenase (GAPDH) were isolated from a lambda gt10 rabbit spleen
cDNA library and sequenced. As predicted from the open reading frame (
ORF) in vitro translation of a sense orientation GAPDH cDNA clone yiel
ded a protein product with a molecular mass of 37 kDa. Rabbit GAPDH ex
hibits a high degree of homology to the mouse, rat, hamster, chicken a
nd human GAPDH on both the nucleotide (nt) and amino acid (aa) levels.