ANTIMALARIAL MACULAR INTOXICATION - A CAS E-REPORT

The clinico-pathological findings in a 17-year-old girl with an <<ceil de boeuf>> maculopathy are reported together with the aetiological el ements involved (hereditary or toxic maculopathy). The case was a seco nd stage typical maculopathy due to antimalarial drugs. These patients were particularly susceptible, probably because of impaired renal fun ction, since the total dose absorbed (140 g. chloroquine) was low. Oph thalmologic monitoring is required to prevent intoxication. Clinical e xamination, angiography and automatic perimetry and contrast sensitivi ty test are needed to detect the first effect of toxicity.