ANTIMALARIAL MACULAR INTOXICATION - A CAS E-REPORT

Citation
F. Ducousso et al., ANTIMALARIAL MACULAR INTOXICATION - A CAS E-REPORT, Journal francais d'ophtalmologie, 18(8-9), 1995, pp. 553-558
Citations number
NO
Categorie Soggetti
Ophthalmology
ISSN journal
01815512
Volume
18
Issue
8-9
Year of publication
1995
Pages
553 - 558
Database
ISI
SICI code
0181-5512(1995)18:8-9<553:AMI-AC>2.0.ZU;2-B
Abstract
The clinico-pathological findings in a 17-year-old girl with an <<ceil de boeuf>> maculopathy are reported together with the aetiological el ements involved (hereditary or toxic maculopathy). The case was a seco nd stage typical maculopathy due to antimalarial drugs. These patients were particularly susceptible, probably because of impaired renal fun ction, since the total dose absorbed (140 g. chloroquine) was low. Oph thalmologic monitoring is required to prevent intoxication. Clinical e xamination, angiography and automatic perimetry and contrast sensitivi ty test are needed to detect the first effect of toxicity.