MECHANISMS OF O-2 SENSING IN THE CAROTID-BODY IN COMPARISON WITH OTHER O-2-SENSING CELLS

Authors
ACKER H XUE DH
Citation
H. Acker et Dh. Xue, MECHANISMS OF O-2 SENSING IN THE CAROTID-BODY IN COMPARISON WITH OTHER O-2-SENSING CELLS, News in physiological sciences, 10, 1995, pp. 211-216
Citations number
15
Categorie Soggetti
Physiology
Journal title
News in physiological sciences → ACNP
ISSN journal
08861714
Volume
10
Year of publication
1995
Pages
211 - 216
Database
ISI
SICI code
0886-1714(1995)10:<211:MOOSIT>2.0.ZU;2-4
Abstract
An NAD(P)H oxidase-generating H2O2 dependent on Po-2 is proposed as an O-2 sensor protein in type I cells of the carotid body, regulating po tassium channel open probability as well as tyrosine hydroxylase gene expression. The proposed signal cascade also is important in other O-2 -sensing cells.