MIVACURIUM CHLORIDE AND MYOTONIC-DYSTROPHY

We describe the successful use of the short-acting, non-depolarizing n euromuscular blocking agent, mivacurium, in a patient with myotonic dy strophy. Increased sensitivity to mivacurium was demonstrated using tr ain-of-four monitoring, with a single dose of mivacurium providing ade quate block for 90 min of surgery. Spontaneous recovery appeared prolo nged with a recovery index (25-75% T1) of 10 min and a recovery time ( 5-95% T1) of 30 min. The use of reversal agents and anticholinergic ag ents was avoided.