FIBROADENOMAS OF THE BREAST - HISTOPATHOLOGICAL DYNAMIC CONTRAST-ENHANCED MR CORRELATION

A total of 22 women with fibroadenomas had preoperative dynamic MR stu dy (T1-weighted images every 47 s after injection of CCL-DOTA). Their age, hormonal status, breast MR studies and histopathological slides w ere retrospectively reviewed. Eleven pre- (n = 2) or post-menopausal ( n = 9) women showed no early contrast enhancement. The absence of earl y contrast enhancement. correlated with hyalin stromal component, Elev en pre- (n = 7) or post-menopausal (n = 4) women showed focal (n = 9) or diffuse (n = 2) early contrast enhancement. Early focal contrast en hancement correlated with myxoid (n = 9), mixed hyalin/myxoid (n = 1) or hyalin (n = 1) fibroadenomas. Early diffuse contrast enhancement of the breast correlated with myxoid (n = 1) or hyalin (n = 1) stromal c omponent associated with proliferative fibrocystic disease of the brea st parenchyma. The presence of contrast enhancement correlated with my xoid fibroadenomas, whereas absence of contrast enhancement correlated with hyalin fibroadenomas. As hyalin fibroadenomas occurs in post-men opausal women, the diagnostic accuracy of dynamic MRI may be improved in this age group.