Mn. Tkachenko et Vf. Sagach, LENGTH-TENSION DEPENDENCE IN VASCULAR SMOOTH-MUSCLE - POSSIBLE PARTICIPATION OF ENDOTHELIN, Experientia, 51(9-10), 1995, pp. 936-940
The results of experiments with isolated strips of rat portal vein, an
d of 'sandwich' experiments involving strips of the portal vein or aor
ta, revealed the involvement of endothelin in the development of myoge
nic reactions of the vascular smooth muscle, observed on distension of
the vascular wall. Released by the endothelial cells, endothelin is c
apable of stimulating the contraction of these muscles.