Gs. Gordon et al., INTRACRANIAL TUMORS DURING THE FIRST 2 YEARS OF LIFE - PRESENTING FEATURES, Archives of Disease in Childhood, 73(4), 1995, pp. 345-347
Between 1979 and 1994, 21 children (nine females, 12 males) with intra
cranial tumours diagnosed before the age of 2 years (range 2-23 months
) were treated at the University Hospital of Wales. The commonest pres
enting symptoms were vomiting (n=9) and unsteadiness (n=8); the common
est presenting sign was enlarged occipitofrontal circumference (>97th
centile in 16 and >90th centile in a further two). In five cases with
signs of raised intracranial pressure, meningitis was the clinical dia
gnosis, and a lumbar puncture was performed. For cases with long delay
s in diagnosis, multiple other disorders had been considered and the s
ignificance of head enlargement had not been recognised. In very early
childhood, intracranial tumours are uncommon and can mimic other diso
rders, especially meningitis. Early neuroimaging is advised when a chi
ld presents with recent onset of neurological symptoms and a dispropor
tionately large head.