AGGRESSIVE ANGIOMYXOMA IN MALES - A REPORT OF 4 CASES

Aggressive angiomyxoma (AAM) is a rare, locally infiltrative but nonme tastasizing tumor of the pelvic and perineal soft tissues that occurs almost exclusively in adult females. The authors describe four cases o f AAM in adult males that arose in the scrotum. There was some histolo gic variation among the tumors. One case was focally hypercellular aro und the blood vessels, two were more densely cellular throughout, and one had cystic degeneration. Three of the tumors were widely infiltrat ive, and one of the four tumors recurred locally. The clinicopathologi c features of these cases are similar to those of AAM occurring in fem ales. In either sex, AAM should be distinguished from benign myxoid tu mors with a low risk of local recurrence and fully malignant myxoid tu mors with distant metastatic potential.