TRANSCRIPTIONAL ANALYSIS OF THE YERSINIA-PESTIS PH-6-ANTIGEN GENE

Authors
PRICE SB FREEMAN MD YEH KS
Citation
Sb. Price et al., TRANSCRIPTIONAL ANALYSIS OF THE YERSINIA-PESTIS PH-6-ANTIGEN GENE, Journal of bacteriology, 177(20), 1995, pp. 5997-6000
Citations number
14
Categorie Soggetti
Microbiology
Journal title
Journal of bacteriology → ACNP
ISSN journal
00219193
Volume
177
Issue
20
Year of publication
1995
Pages
5997 - 6000
Database
ISI
SICI code
0021-9193(1995)177:20<5997:TAOTYP>2.0.ZU;2-N
Abstract
The pH 6 antigen of Yersinia pestis is a virulence protein whose gene, psaA, is positively regulated at the transcriptional level by low pH, mammalian temperature, and an upstream locus, psaE. Low pH appears to be required for initial psaA transcription, although increased temper ature is necessary for full expression of the gene. In addition, psaA is monocistronic and its transcript has a relatively long 5' nontransl ated region.