POPULATION STUDY USING DNA SINGLE LOTUS P ROBES IN WEST AUSTRIA

Allele frequency distribution of the single locus system YNH 24 (n = 3 02), G3 (n = 251), MS 43A (n = 333), and MS 31 (n = 333) was determine d in Western Austria. After digestion with Hinf I, electrophoresis and Southern blotting, the genomic DNA was hybridised with the probes YNH 24, G3, MS 43A, and MS 31. Blood samples were taken from 333 unrelate d caucasians living in the area of Innsbruck, Tyrol, Austria. The frag ment distribution was calculated for each of the 4 single-locus system s. A single fragment pattern, indicating homozygosity, was shown in 9. 93% with YNH 24, 12.45% with G3, 9.61% with MS 43A, and 7.21% with MS 31; the corresponding heterozygosity rates were 90.07%, 87.55%, 90.39% , and 92.79%, respectively. Our data are compared with those from Engl and [18], Germany [3], Greenland [7], and Denmark [14]. Discrimination indices (Table 2) were calculated and statistical parameters (Table 3 ) presented.