SYNTHESIS AND STEREOCHEMISTRY OF CHIRAL 1,3-DIOXANIC COMPOUNDS OBTAINED FROM ALPHA-ALKYLATED BETA-KETOESTERS

Citation
I. Grosu et al., SYNTHESIS AND STEREOCHEMISTRY OF CHIRAL 1,3-DIOXANIC COMPOUNDS OBTAINED FROM ALPHA-ALKYLATED BETA-KETOESTERS, Heterocycles, 41(10), 1995, pp. 2233-2244
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
03855414
Volume
41
Issue
10
Year of publication
1995
Pages
2233 - 2244
Database
ISI
SICI code
0385-5414(1995)41:10<2233:SASOC1>2.0.ZU;2-5
Abstract
1,3-Dioxanic compounds were obtained by the ketalisation reaction of s ome alpha-alkylated beta-ketoesters. The conformational analysis by me ans of H-1- and C-13-nmr investigations showed the anancomeric structu re of the compounds. The axial or the equatorial position of the group s was inferred by N.O.E. experiments. The influence of the chiral carb on atom of the esteric group located at C-2 was studied using the dias tereotopicity of the protons and of the carbon atoms recorded in high field nmr spectra.