OBJECTIVES: To determine the benefit of palliative surgery for patient
s with advanced ovarian cancer and bowel obstruction and to identify c
riteria for selecting patients who are most likely to benefit from pal
liation. DESIGN: A retrospective study of patients treated between 198
2 and 1992. SETTING: A university-affiliated hospital. PATIENTS: Fifty
-three patients with complete and unresolved bowel obstruction caused
by ovarian cancer. INTERVENTION: Surgery for relief of bowel obstructi
on. MAIN OUTCOME MEASURES: Postoperative survival longer than 60 days,
return home and relief of bowel obstruction for longer than 60 days,
factors associated with failure of palliative surgery. RESULTS: Succes
sful palliation was achieved in 27 (51%) patients and was associated w
ith the absence of four prognostic factors: palpable abdominal and pel
vic masses, ascites exceeding 3 L, multiple obstructive sites and preo
perative weight loss greater than 9 kg. Age, time interval between dia
gnosis of ovarian cancer and bowel obstruction, stage of disease at in
itial diagnosis, tumour type and grade, site and degree of obstruction
, presence of gross residual tumour after initial operation and preope
rative use of chemotherapy or radiotherapy did not indicate the succes
s or failure of palliative surgery. CONCLUSIONS: Palliative surgery fo
r bowel obstruction in advanced ovarian cancer can be worthwhile, and
there are four prognostic factors that indicate the likely failure of
palliation.