Inadvertent positive end-expiratory pressure (PEEP) is a potential cau
se of lung overdistension and impaired gas exchange in ventilated infa
nts. It can be extremely difficult to diagnose clinically and if unrec
ognized can be life-threatening. Measurement of long function can lead
to the recognition of inadvertent PEEP, allowing appropriate ventilat
or adjustment with immediate substantial improvement in clinical state
. Lung function measurements can help to optimize ventilation and may
improve clinical outcome.