A CONVENIENT SUPPORT FOR THE SYNTHESIS OF OLIGONUCLEOTIDE 3'-PHOSPHATES

Citation
Va. Efimov et al., A CONVENIENT SUPPORT FOR THE SYNTHESIS OF OLIGONUCLEOTIDE 3'-PHOSPHATES, Bioorganiceskaa himia, 21(8), 1995, pp. 612-616
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
01323423
Volume
21
Issue
8
Year of publication
1995
Pages
612 - 616
Database
ISI
SICI code
0132-3423(1995)21:8<612:ACSFTS>2.0.ZU;2-H
Abstract
A solid phase method for the synthesis of oligonucleotide 3'-phosphate s using a alkylsulfonylethyl controlled pare glass support was develop ed. Using this support, the automated synthesis of oligonucleotides ca n be performed according to standard procedures and programs developed for phosphoroamidite and H-phosphonate methods.