ASYMMETRICALLY SUBSTITUTED MYOINOSITOLS . 37. SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL DERIVATIVES

Authors
SHASTINA NS EINISMAN LI KASHIRICHEVA II STEPANOV AE SHVETS VI
Citation
Ns. Shastina et al., ASYMMETRICALLY SUBSTITUTED MYOINOSITOLS . 37. SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL DERIVATIVES, Bioorganiceskaa himia, 21(8), 1995, pp. 641-650
Citations number
28
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Bioorganiceskaa himia → ACNP
ISSN journal
01323423
Volume
21
Issue
8
Year of publication
1995
Pages
641 - 650
Database
ISI
SICI code
0132-3423(1995)21:8<641:ASM.3S>2.0.ZU;2-4
Abstract
The total synthesis of regioisomeric ac-1,2-dipalmitoylglycerophospho) -4(6)-O-(2-amino- 2-deoxy-beta-D-glucopyranosyl)-sn-myo-inositol and r ac-1,2-dipalmitoylglycerophospho)-sn-myo-inositol is described. The sy nthetic route included stages of consecutive selective protecting-depr otecting of the hydroxyl groups of the inositol ring, the aminoglycosy lation by the oxazoline method, and formation of phosphodiesters of su bstituted myo-inositol derivatives using two modes of the hydrogen-pho sphonate method.