M. Gutschow et U. Neumann, BENZOYLAMINO-6,7-DIMETHOXY-4H-3,1-BENZOXAZIN-4-ONE - SYNTHESIS AND INVESTIGATION OF SERINE-PROTEASE INACTIVATION, Monatshefte fuer Chemie, 126(10), 1995, pp. 1145-1149
Benzoylamino-6,7-dimethoxy-4H-3,1-benzoxazin-4-one was prepared by the
rmal treatment of 2-(3-benzoylthioureido)-4,5-dimethoxybenzoic acid an
d by benzoylation of 2-amino-6,7-dimethoxy-4H-3,1-benzoxazin-4-one. Th
e inactivation of chymotrypsin and human leukozyte elastase by the tit
le compound and 2-benzoylamino-4H-3,1-benzoxazin-4-one is reported.