CUTANEOUS METASTATIC ANGIOSARCOMA WITH A LETHAL OUTCOME, FOLLOWING RADIOTHERAPY FOR A CERVICAL-CARCINOMA

A cutaneous metastatic angiosarcoma was diagnosed in a 79-year-old wom an 19 years after radiotherapy for a carcinoma of the uterine cervix. The diagnosis was confirmed by immunohistochemical staining (factor VI II-related antigen and BMA 120) and electron microscopic examination. Surgical treatment of the large tumour, which was situated in the glut eal region, was not feasible, but electron beam therapy resulted in co mplete remission. However, a further metastasis occurred in the inguin al region, and management by total excision, radiotherapy, and interfe ron-alpha treatment was unsuccessful. The patient died 28 months after the initial diagnosis of the neoplasm.