PROTRACTED CUTANEOUS DISORDERS IN ASSOCIATION WITH LOW CD4(+) LYMPHOCYTE COUNTS

We report two patients with skin disorders usually associated with sev ere immunosuppression, who had low CD4(+) lymphocyte counts but normal immunoglobulin levels, The patients were HIV negative, and had CD4(+) lymphocyte counts just above 300/mm(3), but they presented with cutan eous manifestations of profound immunodeficiency, Idiopathic CD4(+) ly mphocyte deficiency is a recently described syndrome which may present with dermatological disease. We discuss the symptom complex of our pa tients in relationship to the diagnosis of idiopathic CD4(+) lymphocyt e deficiency.