RECALL PHENOMENON WITH THE UNUSUAL PRESENCE OF ECCRINE SQUAMOUS SYRINGOMETAPLASIA

The recall phenomenon is an inflammatory reaction limited to a previou sly X-irradiated field when the patient is treated months or years lat er with certain drugs, Only a few cases have been reported in dermatol ogical journals. We report a patient with lymphoma who was treated wit h low-dose abdominal irradiation and high-dose irradiation to the knee s and who, 2 months later, when chemotherapy was started, developed a pronounced inflammatory reaction limited to the areas treated with hig h-dose irradiation. A skin biopsy specimen showed features of radiatio n damage, marked epidermal changes and extensive eccrine squamous syri ngometaplasia, This: case of the recall phenomenon is of interest beca use we have found that there is apparently a radiation dose threshold for this event, and because this is the first report of its associatio n with eccrine squamous syringometaplasia.