SALIVARY-GLAND SWELLING FOLLOWING NAPROXEN THERAPY

We report allergic sialadenitis as a novel side-effect of naproxen, a non-steroidal anti-inflammatory drug (NSAID), Bilateral swelling of th e major salivary glands and a rash occurred a few days after the patie nt had taken the drug. High-dose systemic corticosteroid therapy was r equired to control the disorder. Because the salivary gland swelling w as not initially recognized as an adverse drug reaction, further doses of naproxen were given on two occasions, with similar results.