Gp. Nielsen et al., CHONDROID LIPOMA, A TUMOR OF WHITE FAT-CELLS - A BRIEF REPORT OF 2 CASES WITH ULTRASTRUCTURAL ANALYSIS, The American journal of surgical pathology, 19(11), 1995, pp. 1272-1276
Chondroid lipoma is a recently described variant of lipoma with unusua
l morphologic features, Although classified as a fatty neoplasm, its p
henotype is uncertain because it has not been determined whether carti
lage is a real component or only simulated by light microscopy and whe
ther the adipocytes demonstrate white or brown fat differentiation, is
sues that can be resolved only by electron microscopy. We present two
cases of chondroid lipoma that ultrastructurally showed abundant intra
cytoplasmic lipid and glycogen and numerous pinocytotic vesicles, char
acteristic of white adipocytes. These findings support the conclusion
that these tumors are composed solely of fat without true cartilage di
fferentiation.