Study objective: To compare the diagnostic sensitivity of a modified A
brams needle pleural biopsy technique (A1) with the standard Abrams (A
2) and Cope needle biopsy methods. The modified Abrams pleural biopsy
technique consisted of suctioning each tissue sample into a syringe wi
thout removing the needle completely from the chest until the completi
on of the entire procedure, Both the standard Abrams and Cope needle t
echniques required needle removal from the chest after each pleural bi
opsy. Design: Retrospective chart analysis. Setting: Community teachin
g hospital affiliated with Stanford University. Patients: Forty-seven
patients (30 men and 17 women) with a mean age of 44.5 years (range, 1
9 to 81 years) who were referred to a pulmonary consultation service f
or pleural biopsy. Interventions: Two of us (C.M.K. and F.T.K.) used t
he modified Abrams technique and two of us (W.A.J. and A.C.C.) used th
e standard Abrams technique, The Cope needle was used as originally de
scribed. Measurements: We recorded the type of pleural biopsy needle a
nd technique used in each patient. Biopsy specimen diameter and number
of tissue samples obtained, final diagnoses, and complications were r
ecorded. Results: The diagnostic sensitivity for tuberculous pleurisy
was 82% for the modified Abrams method, 71% for the standard Abrams me
thod, and 88% for the standard Cope technique (p greater than or equal
to 0.3). There was no difference, in size of tissue sample obtained (
A1 vs A2), number of biopsies, or complications among the three method
s of pleural biopsy. Conclusions: The modified method of Abrams needle
biopsy demonstrates a diagnostic sensitivity for pleural tuberculosis
(82%) that is equivalent to that for the standard Abrams or Cope meth
ods.