T. Kunieda et al., CHROMOSOMAL LOCALIZATION OF A STRAIN-SPECIFIC P53-RELATED SEQUENCE INRAT (RATTUS-NORVEGICUS), Jikken Dobutsu, 44(4), 1995, pp. 301-305
Strain-specific restriction fragments hybridizing to human p53 gene cD
NA, which was detected in only particular strains of inbred rat were r
evealed by Southern blot hybridization of DNAs of various inbred rat s
trains. Chromosomal location of the strain-specific fragments was dete
rmined on rat chromosome I between Kal and Pkc loci by linkage analysi
s using microsatellite marker loci. The fragments were concluded to be
a novel p53-related sequence which is present in particular rat strai
ns and absent from the remaining strains.