CHROMOSOMAL LOCALIZATION OF A STRAIN-SPECIFIC P53-RELATED SEQUENCE INRAT (RATTUS-NORVEGICUS)

Authors
KUNIEDA T KOBAYASHI E IKADAI H IMAMICHI T
Citation
T. Kunieda et al., CHROMOSOMAL LOCALIZATION OF A STRAIN-SPECIFIC P53-RELATED SEQUENCE INRAT (RATTUS-NORVEGICUS), Jikken Dobutsu, 44(4), 1995, pp. 301-305
Citations number
NO
Categorie Soggetti
Veterinary Sciences",Zoology
Journal title
Jikken Dobutsu → ACNP
ISSN journal
00075124
Volume
44
Issue
4
Year of publication
1995
Pages
301 - 305
Database
ISI
SICI code
0007-5124(1995)44:4<301:CLOASP>2.0.ZU;2-6
Abstract
Strain-specific restriction fragments hybridizing to human p53 gene cD NA, which was detected in only particular strains of inbred rat were r evealed by Southern blot hybridization of DNAs of various inbred rat s trains. Chromosomal location of the strain-specific fragments was dete rmined on rat chromosome I between Kal and Pkc loci by linkage analysi s using microsatellite marker loci. The fragments were concluded to be a novel p53-related sequence which is present in particular rat strai ns and absent from the remaining strains.