Globule leukocytes (GLs) infiltrating in transitional cell hyperplasia
and carcinomas of aged BDF, mice were pathologically examined. The in
tracytoplasmic granules of globule leukocytes showed a variety of reac
tivity to histochemical staining for polysaccharides and were ultrastr
ucturally composed of homogeneous electron dense material, occasionall
y containing crystaloids or vesicles. The GL infiltrating in tumor tis
sue is extremely rare,