N. Yokose et al., ACUTE GASTRIC-MUCOSAL LESIONS ASSOCIATED WITH CYTOMEGALOVIRUS-INFECTION IN A NONIMMUNOCOMPROMISED HOST, Internal medicine, 34(9), 1995, pp. 883-885
A 75-year-old woman with epigastric pain and tarry stool was admitted
to our hospital, where upper gastrointestinal endoscopic study reveale
d multiple gastric ulcers. The endoscopic biopsy specimens obtained on
the seventh hospital day disclosed a few typical intranuclear cytomeg
alovirus inclusions. Cytomegalovirus-DNA was detected using polymerase
chain reaction in a biopsy specimen. No immunologic abnormalities wer
e demonstrated by any laboratory tests, While only a few cases of cyto
megalovirus-associated gastric ulcer in non-immunocompromised hosts ha
ve been reported, this entity may be more frequently detected when car
eful histological examination is performed in the active stage rather
than postponed until after healing of the ulcer.