PURPOSE: To compare six MR sequences (plain and gadolinium-enhanced fa
t suppressed T1-weighted spin echo, T2-weighted standard spin echo, fa
t-suppressed and non-fat-suppressed T2-weighted fast spin echo, and in
version-recovery T2-weighted fast spin echo) in their ability to detec
t, delineate, and characterize lesions of the parotid gland. METHODS:
Fifty-eight parotid gland lesions imaged on 47 examinations were retro
spectively evaluated by three blinded observers. Several outcome-relat
ed variables were compared by the above six sequences: imaging time, i
mage quality, anatomic sharpness of parotid space, subjective lesion c
onspicuity, detected abnormality volume, number of individual lesions
or discrete lobulations, conspicuity of invasion into adjacent boundar
ies and structures, and overall diagnostic value. RESULTS: Differences
in the above outcome variables between sequences did not correlate wi
th MR scanner software upgrade level, coil type, or lesion-dependent c
haracteristics. Fat-suppressed fast spin-echo T2-weighted and inversio
n-recovery fast spin-echo T2-weighted sequences resulted in significan
tly higher scores for lesion conspicuity, detected abnormality volume,
and overall diagnostic value. T1-weighted images resulted in the next
highest scores, whereas gadolinium-enhanced T1-weighted and standard
spin-echo T2-weighted sequences performed poorly for most parotid lesi
ons. CONCLUSION: MR imaging of the parotid gland should include fat-su
ppressed, long-repetition-time, fast spin-echo T2-weighted, and T1-wei
ghted sequences. Gadolinium-enhanced images need not be obtained routi
nely.