LATE AGGRESSIVE MENINGIOMA FOLLOWING PROPHYLACTIC CRANIAL IRRADIATIONFOR ACUTE LYMPHOBLASTIC-LEUKEMIA

The clinical, radiological and pathological findings in a 28-year-old female patient who developed aggressive meningioma 20 years after prop hylatic cranial irradiation (PCI) for acute lymphoblastic leukaemia (A LL) are described here. Only four cases of late atypical/aggressive me ningioma following PCI were detected in a thorough search of the liter ature. The high cure rate in childhood ALL, attributable to aggressive chemotherapy and PCI, is capable of inducing secondary brain tumour, including aggressive meningioma.