Eosinophilic pustular folliculitis (Ofuji's disease) is a rare skin di
sease of unknown etiology characterized by infiltrated circinate plaqu
es with sterile follicular pustules in primarily seborrheic areas. Sev
eral therapeutic regimens have been reported to control the disease wi
th inconsistent results. We here report on a patient with Ofuji's dise
ase, who was successfully treated with interferon-alpha 2b.