OBJECTIVE - To compare peak pressures on the sole of the foot in non-i
nsulin-dependent diabetic patients with isolated, unilateral amputatio
ns of the great toe and first metatarsal with the patients' contralate
ral, intact foot. RESEARCH DESIGN AND METHODS - Eleven patients with a
unilateral great toe and partial first metatarsal amputation of at le
ast 6 months duration were evaluated with the F-Scan in-shoe pressure
measurement system. Patients were studied in the same brand and style
of footwear-a thin, rubber-soled, canvas boar shoe. We compared mean p
eak plantar foot pressures under the first metatarsal, lesser metatars
als, lesser toes, and heel in feel with and without a great toe amputa
tion using the Wilcoxon's matched pairs signed-rank test. RESULTS - Pe
ak fool pressures were significantly higher under the first metatarsal
head (P = 0.046), lesser metatarsal heads (P < 0.001), and toes (P <
0.001) in feet with a great toe amputation compared with the contralat
eral foot without an amputation. Pressure under the heel was higher on
the contralateral foot (P < 0.01). CONCLUSIONS - After a great toe am
putation pressure distribution of the foot is significantly altered. B
ecause preamputation risk factors such as peripheral neuropathy, foot
deformity, and limited joint mobility for many of these patients remai
n unchanged, an increase in foot pressures contributes to an increased
risk of reulceration and reamputation in these patients.